Ethical Justification of Involving Human Volunteers in Phase 1 Trials
نویسندگان
چکیده
منابع مشابه
Challenge studies of human volunteers: ethical issues.
There is a long history of medical research that involves intentionally infecting healthy people in order to study diseases and their treatments. Such research-what might be called "human challenge studies"-are an important strand of much current research-for example, in the development of vaccinations. The many international and national guidelines about the proper conduct of medical research ...
متن کاملEthical responsibility of phase 0 trials.
To the Editor: We read with great interest the article by Abdoler et al. (1) on the ethics-based interpretation of phase 0 trials in cancer patients. In our opinion, drugs that consistently show favorable toxicity profile and beneficial therapeutic activity in preclinical models should be tested in anima nobile . This is particularly important for molecular targeted therapies, in which impressi...
متن کاملsynthesis of platinum nanostructures in two phase system
چکیده پلاتین، فلزی نجیب، پایدار و گران قیمت با خاصیت کاتالیزوری زیاد است که کاربرد های صنعتی فراوانی دارد. کمپلکس های پلاتین(ii) به عنوان دارو های ضد سرطان شناخته شدند و در شیمی درمانی بیماران سرطانی کاربرد دارند. خاصیت کاتالیزوری و عملکرد گزینشی پلاتین مستقیماً به اندازه و- شکل ماده ی پلاتینی بستگی دارد. بعضی از نانو ذرات فلزی در سطح مشترک مایع- مایع سنتز شده اند، اما نانو ساختار های پلاتین ب...
Ethical Hacking: The Security Justification
Abstract The state of security on the Internet is poor and progress toward increased protection is slow. This has given rise to a class of action referred to as “Ethical Hacking”. Companies are releasing software with little or no testing and no formal verification and expecting consumers to debug their product for them. For dot.com companies time-to-market is vital, security is not perceived a...
متن کاملLegitimate requests and indecent proposals: matters of justice in the ethical assessment of phase I trials involving competent patients.
The death of Jesse Gelsinger in 1999 during a gene therapy trial raised many questions about the ethical review of medical research. Here, the author argues that the principle of justice is interpreted too narrowly and receives insufficient emphasis and that what we permit in terms of bodily invasion affects the value we place on individuals. Medical research is a societally supported activity....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bangladesh Journal of Bioethics
سال: 2017
ISSN: 2078-1458,2226-9231
DOI: 10.3329/bioethics.v8i2.34476